Plant Pathology and Microbiology

Ph.D. Molecular Biology, University of Wisconsin

B.A. Biology, Carleton College

MICRO 408/508: Virology

Positive sense RNA viruses of plants and insects, RNA structure and function, Translation mechanisms

Wang Z, Kraft JJ, Hui A, Miller WA (2010) Structural plasticity of Barley yellow dwarf virus-like cap-independent translation elements in four genera of plant viral RNAs. Virology 402, 177-186.

Liu S, Sivakumar S, Sparks WO, Miller WA, Bonning BC (2010) A peptide that binds the pea aphid gut impedes entry of Pea enation mosaic virus into the aphid hemocoel. Virology 401, 107-116.

Bonning BC, Miller WA (2010) Dicistroviruses. Annu Rev Entomol 55, 129-150.

Miller WA, Giedroc DP (2010) Ribosomal frameshifting in decoding plant viral RNAs. In Recoding: Expansion of Decoding Rules Enriches Gene Expression (Nucleic Acids and Molecular Biology vol. 24) (J Atkins, R Gesteland eds.) Springer, New York. pp. 193-220.

Wang, Z, Treder K, Miller WA (2009) Structure of a viral cap-independent translation element that functions via high affinity binding to the eIF4E subunitof eIF4F. J Biol Chem 284, 14189–14202. DOI 10.1074/jbc.M808841200

Sivakumar S, Harrison RL, Liu S, Miller WA, Bonning BC (2009) Baculovirus-expressed virus-like particles of Pea enation mosaic virus vary in size and encapsidate baculovirus mRNAs (2009) Virus Research 139, 54–63. DOI 10.1016/j.virusres.2008.10.002

Liu S, Sivakumar S, Wang Z, Bonning BC, Miller WA (2009) The readthrough domain of pea enation mosaic virus coat protein is not essential for virus stability in the hemolymph of the pea aphid. Arch Virol154, 469–479. DOI 10.1007/s00705-009-0327-7

Boyapalle S, Beckett RJ, Pal N, Miller WA, Bonning BC (2008) Infectious genomic RNA of Rhopalosiphum padi virus transcribed in vitro from a full-length cDNA clone. Virology 375, 401-411.

Chung BY-W, Miller WA, Atkins JF, Firth AE (2008) An overlapping essential gene in the Potyviridae. Proc Natl Acad Sci USA 105, 5897-5902.

Salem NM, Miller WA, Rowhani A, Golino DA, Moyne A-L, Falk BW (2008) Rose spring dwarf-associated virus has RNA structural and gene-expression features like those of Barley yellow dwarf virus. Virology 374, 354-360.

Treder K, Pettit Kneller EL, Allen EM, Wang Z, Browning KS, Miller WA (2008) The 3’ cap-independent translation element of Barley yellow dwarf virus binds eIF4F via the eIF4G subunit to initiate translation. RNA 14, 134-147.

Miller WA, Wang Z, Treder K (2007) The amazing diversity of cap-independent translation elements in the 3’-untranslated regions of plant viral RNAs. Biochemical Society Transactions 35, 1629-1633.

Pal, N., Boyapalle, S., Beckett, R., Miller, W.A. and Bonning, B.C. 2007. A baculovirus-expressed dicistrovirus that is infectious to aphids. Journal of Virology 81 9339–9345.

Shen R, Miller WA (2007) Structures required for poly(A) tail-independent translation overlap with, but are distinct from, cap-independent translation and RNA replication signals at the 3' end of Tobacco necrosis virus RNA. Virology 358, 448-458.

Boyapalle S, Pal N, Miller WA, Bonning BC (2007) A glassy-winged sharpshooter cell line supports replication of Rhopalosiphum padi virus (Dicistroviridae). Journal of Invertebrate Pathology94, 130139.

Shen R, Rakotondrafara AM, Miller WA (2006) trans regulation of cap-independent translation by a viral subgenomic RNA. Journal of Virology 80, 10045-10054.

Rakotondrafara AM, Polacek C, Harris E, Miller WA (2006) Oscillating kissing stem-loop interactions mediate 5' scanning-dependent translation by a viral 3' cap-independent translation element. RNA 12, 1893-1906.

Dreher TW, Miller WA (2006) Translational control of positive strand RNA plant viruses. Virology 344, 185-197.

Pettit Kneller EM, Rakotondrafara AM, Miller WA (2006) Cap-independent translation of plant viral RNAs. Virus Research 119, 63-75.

Miller WA, White KA (2006) Control of plant virus gene expression and replication by long-distance RNA-RNA interactions. Annual Review of Phytopathology 44, 447-467.

Shen R, Miller WA (2004) Subgenomic RNA as a riboregulator: Negative regulation of virus replication by Barley yellow dwarf virus subgenomic RNA 2. Virology 327, 196-205.

Song SI, Miller WA (2004) Cis and trans requirements for rolling circle replication of a satellite RNA. J Virol 78, 3072-3082.

Shen R, Miller WA (2004) The 3’ untranslated region of Tobacco necrosis virus RNA contains a Barley yellow dwarf virus-like cap-independent translation element. J Virol 78, 4655-4664.

Barry JK, Miller WA (2002) A -1 ribosomal frameshift element that requires base pairing across four kilobases suggests a mechanism of regulating ribosome and replicase traffic on a viral RNA. Proc Natl Acad Sci USA 99, 11133-11138.

Miller WA, Beckett R, Liu, S (2002) Barley yellow dwarf virus: Luteoviridae or Tombusviridae? Molecular Plant Pathol 3, 177-183 293, 781-793.

Guo L, Allen EM, Miller WA (2001) Base-pairing between untranslated regions facilitates translation of an uncapped, non-polyadenylated viral mRNA. Molecular Cell 7, 1103-1109 .