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The Baum Lab is located in Ames, Iowa, in the heart of the heartland, approximately 35 miles north of Des Moines, Iowa's capital. Ames is a city of more than 50,000 people, with a major university, yet still maintains a small town atmosphere. For more information about Ames, please visit this site.


Jason Noon Graduates

May 27, 2016

The Baum lab would like to announce the graduation of Dr. Jason Noon from his PhD program at Iowa State University. During his time in the Baum lab, Jason was involved in identifying and functionally characterizing the roles of Heterodera glycines effectors during parasitism of soybean, and on the transcriptional reprogramming of soybean root cells during syncytium formation. Read more about Jason Noon Graduates

Genome Informatics Facility (GIF)

The Genome Informatics Facility serves as a centralized resource of expertise on the application of emerging sequencing technologies and open source software as applied to biological systems. Its mission is to integrate this knowledge into pipelines that are easy to understand and use by faculty, staff and students to enable the transformation of ‘big data’ into data that dramatically accelerates our understanding of biology and evolutionary processes.

Gennady Pogorelko gives a talk at the 2016 Society of Nematology/ONTA meeting in Montreal, July 2016

October 24, 2016

Gennady Pogorelko gave a talk entitled "Heterodera Effector Protein 4E02 is a Powerful Regulator of Plant Susceptibility" during the 2016 joint meeting of the Society of Nematologists and the Organization of Nematologists of Tropical America.   The meeting was held in Montreal, Canada July 17-21, 2016. Read more about Gennady Pogorelko gives a talk at the 2016 Society of Nematology/ONTA meeting in Montreal, July 2016

Thomas Baum and Tom Maier attend the 2016 European Society of Nematologists meeting in Braga, Portugal

October 24, 2016

Thomas Baum and Tom Maier traveled to Braga, Portugal in September 2016 to attend the European Society of Nematologist's 32nd Symposium.   While attending the meeting, Baum and Maier also participated in a workshop to discuss the current state of the progress in plant-parasitic nematode transformation. Read more about Thomas Baum and Tom Maier attend the 2016 European Society of Nematologists meeting in Braga, Portugal

About Our Lab

Research in the Baum lab focuses on the compatible interaction between cyst nematodes and their hosts with particular emphasis on the soybean cyst nematode (Heterodera glycines) and the sugar beet cyst nematode (H. schachtii).  To a smaller extent, some projects are dealing with the root-knot nematodes, Meloidogyne spp.  This group of so-called sedentary endoparasitic phytonematodes represents the most damaging group of plant-parasitic nematode and is responsible for billions of annual losses.  We are working to understand the molecular, genetic, and biochemical events of successful plant parasitism, the so-called compatible interaction. For this purpose, we are characterizing the signal transduction events leading to successful nematode establishment and parasitism with an ever increasing emphasis on cell biological approaches. These efforts include characterization of changes in plant and nematode gene expression during the different phases of parasitism, functional characterization of genes involved in the plant-nematode interaction, and most importantly, the study of nematode effector proteins, a group of molecules we call parasitism proteins.

Diagram of a nematode attacking a plant

We are frequently using the Arabidopsis thaliana model system because this plant is successfully infected by H. schachtii and gives us access to a wide variety of genetic and molecular resources.  Ultimately, understanding the compatible plant-nematode interaction will allow us to interfere with parasitism through genetic engineering of host plants in order to solve major agricultural and horticultural problems.  Currently, we are using an RNAi-based approach to decrease plant susceptibility to nematodes. Read more about About Our Lab